Analysis of a long-term outbreak of extensively drug-resistant Pseudomonas aeruginosa using whole-genome sequencing and a novel Time-Place-Sequence algorithm: a molecular epidemiological study
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Analysis of a long-term outbreak of XDR Pseudomonas aeruginosa: a molecular epidemiological study.
OBJECTIVES Here we report on a long-term outbreak from 2009 to 2012 with an XDR Pseudomonas aeruginosa on two wards at a university hospital in southern Germany. METHODS Whole-genome sequencing was performed on the outbreak isolates and a core genome was constructed for molecular epidemiological analysis. We applied a time-place-sequence algorithm to improve estimation of transmission probabi...
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